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The apical junctional complexes, roles, and dysfunctions

✍ Scribed by Jean-Claude Hervé


Book ID
116274797
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
94 KB
Volume
1788
Category
Article
ISSN
0005-2736

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Tight junctions (TJ) and adherens junctions (AJ) regulate cell-cell adhesion and barrier function of simple polarized epithelia. These junctions are positioned in the apical end of the lateral plasma membrane and form the socalled apical junctional complex (AJC). Although initially seen as purely st