𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The antitumor activities of celecoxib are mediated primarily through inhibition of pge2 production

Book ID
117659566
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
137 KB
Volume
38
Category
Article
ISSN
0959-8049

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Antitumor action of the PKC activator gn
Antitumor action of the PKC activator gnidimacrin through cdk2 inhibition
✍ Mitsuzi Yoshida; Weijian Feng; Kazuto Nishio; Minako Takahashi; Yuji Heike; Naga πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 131 KB

Daphnane-type diterpene gnidimacrin (NSC252940), isolated from a Chinese plant, exhibited antitumor activity against murine leukemias and solid tumors. At concentrations of 10 -9 to 10 -10 M, this agent strongly inhibited the growth of human tumor cell lines. In sensitive human leukemia K562 cells,

PGE2-mediated upregulation of iNOS in mu
PGE2-mediated upregulation of iNOS in murine breast cancer cells through the activation of EP4 receptors
✍ Alexander V. Timoshenko; Peeyush K. Lala; Chandan Chakraborty πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 French βš– 200 KB

## Abstract We report here that endogenous prostaglandin E~2~ (PGE~2~) resulting from cyclooxygenase (COX)‐2 expression in a highly metastatic murine breast cancer cell line C3L5 upregulates IFN‐γ + LPS‐induced nitric oxide (NO) synthase (iNOS) expression and NO production. This action of PGE~2~ is