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The antiteratogenic effects of hypo- and hyperthermia in trypan blue-treated chick embryos

✍ Scribed by Gary L. Kolesari; Stanley Kaplan


Book ID
118872772
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
549 KB
Volume
38
Category
Article
ISSN
0012-1606

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Physiological effects of trypan blue on
✍ Hoffman, David J. ;Ramm, Gordon M. πŸ“‚ Article πŸ“… 1972 πŸ› John Wiley and Sons 🌐 English βš– 415 KB πŸ‘ 1 views

## Abstract Ten‐day chick embryos (1) received yolk sac injections of 0.1 ml of 1.5% trypan blue in sterile saline, (2) received 0.1 ml of sterile saline or (3) were handled and returned to the incubator and examined five hours later. Trypan blue treated embryos exhibited decreased survival rate an

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Treatment of chick embryos early in development with the teratogen, trypan blue, results in a high incidence of rumplessness at later developmental stages. Experiments were conducted to discover the causative events between dye administration and rumplessness. Initially, 167 two-day embryos were tre