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The antinociceptive effect of a leukotriene receptor antagonist and a dual inhibitor of arachidonic acid by two tests in mice

✍ Scribed by S. Gök; N. Gacar; N. Erciyes; N.I. Kalyoncu


Book ID
119179765
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
137 KB
Volume
31
Category
Article
ISSN
1043-6618

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Antinociceptive effects of a novel dual
✍ Robert B. Raffa; Charlene D. Connelly; Rebecca P. Martinez; James J. Schupsky; D 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 875 KB

## Abstract Tepoxalin is a novel dual inhibitor of cyclooxygenase (CO) and lipoxygenase (LO) pathways of arachidonic acid metabolism with a relative lack of gastrointestinal side effects within its preclinical therapeutic dose range. The present study investigated the antinociceptive action of tepo