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The antimicrobial peptide cathelicidin enhances activation of lung epithelial cells by LPS

โœ Scribed by Shaykhiev, R.; Sierigk, J.; Herr, C.; Krasteva, G.; Kummer, W.; Bals, R.


Book ID
120611880
Publisher
The Federation of American Societies for Experimental Biology
Year
2010
Tongue
English
Weight
365 KB
Volume
24
Category
Article
ISSN
0892-6638

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__p__VEC is a cellโ€penetrating peptide derived from the murine vascular endothelialโ€cadherin protein. To evaluate the potential of __p__VEC as antimicrobial peptide (AMP), we synthesized __p__VEC and its analogs with Trp and Arg/Lys substitution, and their antimicrobial and lipopolysaccharide (LPS)โ€