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The antileukaemic activity of 5-Aza-2 deoxycytidine (Aza-dC) in patients with relapsed and resistant leukaemia

✍ Scribed by Richel, DJ; Colly, LP; Kluin-Nelemans, JC; Willemze, R


Book ID
109836596
Publisher
Nature Publishing Group
Year
1991
Tongue
English
Weight
823 KB
Volume
64
Category
Article
ISSN
0007-0920

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## Abstract ## BACKGROUND General and site‐specific DNA methylation is associated with tumor progression and resistance in several cancers, including chronic myelogenous leukemia (CML). Decitabine is a hypomethylating agent that has shown encouraging preliminary anti‐CML activity. This study evalu