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The antihypertensive and cardioprotective effects of (−)-MJ-451, an ATP-sensitive K+ channel opener

✍ Scribed by Yen-Mei Lee; Mao-Hsiung Yen; Yen-Yen Peng; Jeon-Rong Sheu; Yao-Chang Chen; Ming-Jyh Chang; Chen-Yu Cheng

Book ID
114012982
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
312 KB
Volume
397
Category
Article
ISSN
0014-2999

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✍ Taku Taguchi; Tomo-oki Satoh; Mikiko Mori; Satoshi Takeo 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 154 KB

The cardioprotective effects of YM934, an ATP-sensitive potassium channel opener (KCO), on isolated canine cardiomyocytes were examined. Exposure of isolated canine cardiomyocytes to YM934 (10 µM) resulted in an increase of potassium channel opening activity in whole cell patch clamp technique. Glib