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The antifibrotic effect of TGF-β1 siRNAs in murine model of liver cirrhosis

✍ Scribed by Kyung-Hyun Kim; Hyun-Chul Kim; Mee-Yul Hwang; Hoon-Kyu Oh; Tae-Sung Lee; Young-Chae Chang; Ho-Jung Song; Nam-Hee Won; Kwan-Kyu Park

Book ID: 116292635
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 943 KB
Volume: 343
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2006.03.087

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## Abstract Schistosomiasis mansoni disseminated worm eggs in mice and humans induce granulomatous inflammations and cumulative fibrosis causing morbidity and possibly mortality. In this study, intrahepatic and I.V. injections of a double‐stranded oligodeoxynucleotide decoy containing the TGF‐β reg