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The anti-platelet and anti-thrombotic effects of FK633, a peptide-mimetic GPIIbIIIa antagonist

✍ Scribed by Toshiaki Aoki; Dermot Cox; Kayoko Senzaki; Jiro Seki; Akihito Tanaka; Hisashi Takasugi; Yukio Motoyama


Book ID
116087094
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
1018 KB
Volume
81
Category
Article
ISSN
0049-3848

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## Abstract The anti‐platelet properties of FK419 ((S)‐2‐acetylamino‐3‐[(R)‐[1‐[3‐(piperidin‐4‐yl)propionyl]piperidin‐3‐ylcarbonyl] amino]propionic acid), a novel non‐peptide GPIIb/IIIa antagonist, were compared in a variety of experimental settings, both in vitro and in vivo, with other GPIIb/IIIa