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The ansamycin antibiotic actamycin. II. Determination of the structure using carbon-13 biosynthetic labelling

โœ Scribed by I.A. McDonald; R.W. Rickards


Publisher
Elsevier Science
Year
1981
Tongue
French
Weight
180 KB
Volume
22
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


The structure of the ansamycin antibiotic actamycin is defined by analysis of biosynthetically 13C-enriched and natural abwxlance n.m.r. spectra, in conjunction with previous degradative evidence.


๐Ÿ“œ SIMILAR VOLUMES


The ansamycin antibiotic actamycin. I. D
โœ M.S. Allen; I.A. McDonald; R.W. Rickards ๐Ÿ“‚ Article ๐Ÿ“… 1981 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 206 KB

The ansamycin antibiotic actamycin is shown to contaiti the meZeus (2a) or (2b) and the ansa bridge segments (7), ( 8), 191 and 110) by spectroscopic and degradative studies in conjunction with deuteriwn labelzing.

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โœ Stephen Hanessian; Ghanshyam Patil ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 232 KB

Spectroscopic techniques have played an increasingly important role in the structure elucidation of the aminoglycoside antibiotics 1 during the past decade. Initially using mass spectrometry and more recently in combination