Grb2-SH3 ligand inhibits the growth of H
β
Brunilde Gril; Michel Vidal; Franck Assayag; Marie-France Poupon; Wang-Qing Liu;
π
Article
π
2007
π
John Wiley and Sons
π
French
β 633 KB
## Abstract HER2 represents an important signaling pathway in breast and other cancers. Herceptin has demonstrated clinical activity, but resistance is common. Thus, new therapeutic approaches to the HER2 pathway are needed. Grb2 is an adaptor protein involved in Rasβdependent signaling induced by