The ammonium-promoted formylation of indoles by DMSO and H2O
โ Scribed by Fei, Haiyang; Yu, Jintao; Jiang, Yan; Guo, Huan; Cheng, Jiang
- Book ID
- 121209609
- Publisher
- Royal Society of Chemistry
- Year
- 2013
- Tongue
- English
- Weight
- 381 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1477-0520
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## Abstract magnified image A new, facile, efficient, โgreenโ and chemoselective procedure for the synthesis of indole derivatives has been developed with pulverizationโactivation method catalyzed by Bi(NO~3~)~3~ยท5H~2~O (PAMCโ Bi(NO~3~)~3~ยท5H~2~O) through grinding of indoles with aldehydes or Mich
The valuable new synthetic intermediates, ethyl 4-, 6-and 7-formyl-1H-indole-2-carboxylates (10, 11, 12) were prepared from 2-ethoxycarbonyl-1H-indole-4-, 6-and 7-methanesulfonic acids (1, 2, 3), respectively. The transformation of sulfomethyl group to formyl function was accomplished through elimin