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The Amino Acid Following an Asn-X-Ser/Thr Sequon Is an Important Determinant of N-Linked Core Glycosylation Efficiency

✍ Scribed by Mellquist, J. L.; Kasturi, L.; Spitalnik, S. L.; Shakin-Eshleman, S. H.


Book ID
120338569
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
66 KB
Volume
37
Category
Article
ISSN
0006-2960

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N-glycosylation efficiency is determined
✍ Manuel Bañó-Polo; Francesca Baldin; Silvia Tamborero; Marc A. Marti-Renom; Ismae 📂 Article 📅 2010 🏛 Cold Spring Harbor Laboratory Press 🌐 English ⚖ 700 KB

## Abstract __N__‐glycosylation is the most common and versatile protein modification. In eukaryotic cells, this modification is catalyzed cotranslationally by the enzyme oligosaccharyltransferase, which targets the β‐amide of the asparagine in an Asn‐Xaa‐Ser/Thr consensus sequon (where Xaa is any