𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The American Society for Mass Spectrometry


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
371 KB
Volume
7
Category
Article
ISSN
1044-0305

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✦ Synopsis


Trace analysis can employ various ionization and data processing techniques for acceptable detection, confirmation and quantitation.

Consequently, a widely differing comprehension has evolved in the scientific literature of how to calculate the detection limit and what constitutes unambiguous confirmation. At the same time, it is clear that regulatory agencies, courts and the public expect analytical results to be defensible and interpretable in only one way.

The workshop will strive to develop a consensus set of criteria and/or guidelines which can be used to develop and validate methods. These guidelines will address issues of specificity, accuracy, reproducibility, limit of detection and applicability. The guidelines will be formulated from statistical theory, regulatory examples and practical experiences using a wide variety of MS and MS/MS techniques.

Speakers Topics


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