The American Society for Mass Spectrometry
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 371 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1044-0305
No coin nor oath required. For personal study only.
β¦ Synopsis
Trace analysis can employ various ionization and data processing techniques for acceptable detection, confirmation and quantitation.
Consequently, a widely differing comprehension has evolved in the scientific literature of how to calculate the detection limit and what constitutes unambiguous confirmation. At the same time, it is clear that regulatory agencies, courts and the public expect analytical results to be defensible and interpretable in only one way.
The workshop will strive to develop a consensus set of criteria and/or guidelines which can be used to develop and validate methods. These guidelines will address issues of specificity, accuracy, reproducibility, limit of detection and applicability. The guidelines will be formulated from statistical theory, regulatory examples and practical experiences using a wide variety of MS and MS/MS techniques.
Speakers Topics
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Two mass spectrometry meetings in May and June provided opportunities for interested parties to discuss the multiplicity of terms used to designate the technique of continuously measuring, through time, the intensities of one or more preselected ions. Terms designating the associated experimental re