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The alternative oxidase, a tool for compensating cytochrome c oxidase deficiency in human cells

✍ Scribed by Emmanuel P. Dassa; Eric Dufour; Sergio Goncalves; Howard T. Jacobs; Pierre Rustin


Book ID
110903721
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
517 KB
Volume
137
Category
Article
ISSN
0031-9317

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Defects of the mitochondrial respiratory chain often involve dysfunction of cytochrome \(c\) oxidase, the terminal component of this chain. We have developed a microassay, suitable for various cell types, which can be carried out in microwell plates. This assay has advantages over the traditional sp