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The Allenic Pauson−Khand Reaction in Synthesis

✍ Scribed by Benito Alcaide; Pedro Almendros


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
189 KB
Volume
2004
Category
Article
ISSN
1434-193X

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## Abstract The carbonyldicobalt‐mediated alkyne/allene/CO cocyclization gives 4‐alkylidenecyclopentenones as the major [2+2+1] cycloadducts. The regio‐ and stereoselectivities depend mainly on the substitution pattern of both the alkyne and the allenic moieties, which can be rationalized using the