The alkaloids of fungi IV. Alkaloid biosynthesis in Aspergillus flavus

✍ Scribed by Dr. L. A. R. Sallam; A. H. El-Refai; N. Naim

• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 328 KB
• Volume: 11
• Category: Article
• ISSN: 0233-111X
• DOI: 10.1002/jobm.19710110210

✦ Synopsis

The changes of the composition of the alkaloid fraction of Aspergillus flaous during t h e different growth phases were studied. The clavines, agroclavines and elymoclavines were formed in comparatively higher yields during the early phase of growth. thereafter their concentration gradually decreased while the production of the peptide alkaloid, ergokryptine, was enhanced. Ergokryptine proved to be the principal product at, the late phase of growth. The supplementation of a mixture of acetate and m-tryptophan to the culture medium stimulated the growth and the formation of lipids and alkaloids.