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The alignment of clusters using large-scale simulations

✍ Scribed by Lesley I. Onuora; Peter A. Thomas


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
176 KB
Volume
319
Category
Article
ISSN
0035-8711

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Sequence alignment programs such as BLAST and PSI-BLAST are used routinely in pairwise, profile-based, or intermediate-sequencesearch (ISS) methods to detect remote homologies for the purposes of fold assignment and comparative modeling. Yet, the sequence alignment quality of these methods at low se