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The age-associated decrease in the amount of amplifiable full-length mitochondrial DNA in human skeletal muscle

✍ Scribed by Sergey A. Kovalenko; George Kopsidas; Mohammed M. Islam; Damien Heffernan; Jennifer Fitzpatrick; Aphrodite Caragounis; Elliot Gingold; Anthony W. Linnane


Book ID
111742993
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
611 KB
Volume
46
Category
Article
ISSN
1521-6543

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Age-associated mitochondrial DNA deletio
✍ Eimon, Peter M. ;Chung, Susan S. ;Lee, Connie M. ;Weindruch, Richard ;Aiken, Jud πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 747 KB

The abundance of mitochondrial DNA (mtDNA) deletions has been shown to increase with age in a number of species and may contribute to the aging process. Estimating the total mtDNA deletion load of an individual is essential in evaluating the potential physiological impact. In this study, we compared