𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The adrenergic receptor agonist, clonidine, potentiates the anti-parkinsonian action of the selective κ-opioid receptor agonist, enadoline, in the monoamine-depleted rat

✍ Scribed by M P Hill; J M Brotchie

Book ID
110004680
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
238 KB
Volume
128
Category
Article
ISSN
0007-1188

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Kappa-opioid receptor agonists increase
Kappa-opioid receptor agonists increase locomotor activity in the monoamine-depleted rat model of parkinsonism
✍ Neill R. Hughes; Alexander T. McKnight; Geoffrey N. Woodruff; Michael P. Hill; A 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 607 KB

## Abstract Excessive glutamate transmission in the basal ganglia is a major factor in the neural mechanisms underlying parkinsonian akinesia. Activation of K opioid receptors causes a presynaptic reduction in glutamate release. K opioid receptors are concentrated in those regions of the basal gang

Indirect dopamine agonists augment the l
Indirect dopamine agonists augment the locomotor activating effects of the κ-opioid receptor agonist U-50,488 in preweanling rats
✍ Sanders A. McDougall; Audrey L. Rodarte-Freeman; Arbi Nazarian 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 144 KB 👁 1 views

## Opioid receptor agonists (e.g.,488) increase the locomotor activity of preweanling rats, while the same drugs depress the locomotor activity of adults. Curiously, direct stimulation of dopamine (DA) D 2 -like receptors fully attenuates the U-50,488-induced locomotor activity of preweanling rats

Repeated administration of the selective
Repeated administration of the selective kappa-opioid receptor agonist U-69593 increases stimulated dopamine extracellular levels in the rat nucleus accumbens
✍ José Antonio Fuentealba; Katia Gysling; Karin Magendzo; María Estela Andrés 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 244 KB

Reinforcing properties of drugs of abuse are reduced by the coadministration of kappa opioid receptor (KOR) agonists. This effect is related to the inhibition of dopamine (DA) release in the nucleus accumbens (NAc) produced by the acute administration of KOR agonists. The present study was undertake