The immune system is a delicately balanced network of interacting cells. In recent years, the concept of immune regulation/suppression has been firmly established, and both natural and induced regulatory cells play vital roles in protection from autoimmune disease. Recent work has revealed the diver
✦ LIBER ✦
The adjuvant effect of TLR agonists on CD4+ effector T cells is under the indirect control of regulatory T cells
✍ Scribed by Aurélie Olivier; Alexander Sainz-Perez; Hui Dong; Tim Sparwasser; Laleh Majlessi; Claude Leclerc
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 449 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0014-2980
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## Abstract Regulatory T cells (Treg) are vital in maintaining the homeostasis of immune reactions. In chronic infections, such as schistosomiasis, it remains unclear whether engagement of the TLR family is required to induce Treg activity. Thus, we performed __in vivo__ studies using TLR2^–/–^ mic