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The adjuvant activity of synthetic N-acetylmuramyl-dipeptide: Evidence of initial target cells for the adjuvant activity

โœ Scribed by Kazuhisa Sugimura; Masanao Uemiya; Ikuo Saiki; Ichiro Azuma; Yuichi Yamamura


Book ID
115811693
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
942 KB
Volume
43
Category
Article
ISSN
0008-8749

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## Abstract The mechanism of adjuvant activity of the synthetic glycopeptide Nโ€acetylmuramylโ€Lโ€alanylโ€Dโ€isoglutamine or muramyl dipeptide (MDP) was studied using __in vitro__ plaqueโ€forming cell (PFC) response to sheep erythrocytes (SRBC). Addition of MDP to DBA/2 mouse spleen cell cultures resulte