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The additive inhibitory effect of cyclosporine A and prednisolone on cell proliferation and interleukin-2 production

✍ Scribed by Manfro, R.C.; Pohanka, E.; Benet, L.Z.; Garovoy, M.R.

Book ID: 121986870
Publisher: Elsevier Science
Year: 1988
Tongue: English
Weight: 141 KB
Volume: 23
Category: Article
ISSN: 0198-8859
DOI: 10.1016/0198-8859(88)90200-5

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Both glucocorticoids and cyclosporine are used to prevent rejection in organ transplant recipients. However, long-term treatment with these drugs is known to induce hyperlipidemia and premature development of atherosclerosis. In previous studies, we have shown that the immunosuppressive drug cyclosp