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The adaptive response of E. coli to low levels of alkylating agent: The role of polA in killing adaptation

โœ Scribed by Jeggo, Penelope ;Defais, Martine ;Samson, Leona ;Schendel, Paul

Publisher
Springer
Year
1978
Tongue
English
Weight
592 KB
Volume
162
Category
Article
ISSN
0026-8925

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The adaptive-response is an inducible repair system of E. coli which reduces the mutagenic and cytotoxic effects of alkylation damage (Samson and Cairns, 1977). In adapted cells (cells exposed to sublethal doses of alkylating agents) the induction of W-reactivation and W-mutagenesis by alkylating ag