17β-estradiol protects against hypoxic/i
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Bettina Gerstner; Joan Lee; Tara M. DeSilva; Frances E. Jensen; Joseph J. Volpe;
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Article
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2009
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John Wiley and Sons
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English
⚖ 345 KB
## Abstract Developing oligodendrocytes (pre‐OLs) are highly vulnerable to hypoxic‐ischemic injury and associated excitotoxicity and oxidative stress. 17β‐Estradiol plays an important role in the development and function of the CNS and is neuroprotective. The sudden drop in circulating estrogen aft