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The ADAM gene family: surface proteins with adhesion and protease activity

✍ Scribed by Paul Primakoff; Diana G Myles


Book ID
114174401
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
126 KB
Volume
16
Category
Article
ISSN
0168-9525

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The fertilin a and b genes (Ftna and Ftnb, respectively) encode a sperm surface heterodimer that functions in sperm-egg fusion. They are the first identified members of a large gene family coding for multidomain membrane proteins (ADAMs) that include A Disintegrin And Metalloprotease domain. In this