## Abstract Until the 16th day of gestation the intravenous LD~50~ of Cd^2+^ in the pregnant WistarβPorton rat is higher, but not significantly different from that (1.8 mg Cd^2+^ per kg body weight) in nulliparous females. At 20 days it is 1.1 mg Cd^2+^ kg per body weight. This decrease is related
The acute toxicity and teratogenicity of nickel in pregnant rats
β Scribed by A. Mas; D. Holt; M. Webb
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 534 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0300-483X
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Mercuric mercury (Hg2+), when injected IV into the pregnant Wistar rat, is retained mainly in the maternal compartment and uptake by the conceptuses is small. Thus if the dose is based on total body weight, the maternal body burden, particularly in late gestation, is greater than the whole body burd
The rat foetus, in contrast with the maternal liver and placenta, has little or no ability t o hydrolyse di-(2-methoxyethy1)-phthalate (DMEP) to mono-2-methoxyethylphthalate (MMEP). At short times after the administration of DMEP to the dam on the 14th day of gestation, however, both the di-and mono