The activity of the pentose phosphate pathway is increased in response to oxidative stress in Alzheimer's disease
β Scribed by A. M. Palmer
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 122 KB
- Volume
- 106
- Category
- Article
- ISSN
- 1435-1463
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## Abstract A depletion of large cholinergic neurons in the nucleus basalis of Meynert is a consistent finding in Alzheimer's disease (AD). The nucleus basalis of Meynert also contains interneurons and afferents that may modulate its functioning. In the present study we examined neurochemical marke
## Abstract Two of the earliest manifestations of the selective neurodegeneration that occurs in Alzheimer's disease (AD) involve the oxidative modification of various biomacromolecules and the reexpression of a multitude of cell cycleβrelated proteins. Taken together with the proximal and ectopic