Increased activity of guanosine 3′-5′-cy
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Paolo Angeli; Wladimiro Jiménez; Rosalia Veggian; Silvano Fasolato; Roberta Volp
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Article
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2000
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John Wiley and Sons
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English
⚖ 136 KB
A possible defect of guanosine 3Ј-5Ј-cyclic monophosphate (cGMP) content in the renal tissue caused by an increased activity of cGMP phosphodiesterase (PDE) has, so far, not been evaluated in the pathogenesis of renal resistance to endogenous natriuretic peptides (ENP) in cirrhosis with ascites. To