The active site protonation states of perdeuterated Toho-1 β-lactamase determined by neutron diffraction support a role for Glu166 as the general base in acylation

✍ Scribed by Stephen J. Tomanicek; Kathy K. Wang; Kevin L. Weiss; Matthew P. Blakeley; Jonathan Cooper; Yu Chen; Leighton Coates

• Book ID: 113622361
• Publisher: Elsevier Science
• Year: 2010
• Tongue: English
• Weight: 675 KB
• Volume: 585
• Category: Article
• ISSN: 0014-5793
• DOI: 10.1016/j.febslet.2010.12.017