The action potential of frog nerve as affected by temperature, narcosis, and stimulation frequency
✍ Scribed by Sjodin, R. A. ;Mullins, L. J.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1958
- Tongue
- English
- Weight
- 682 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0095-9898
No coin nor oath required. For personal study only.
✦ Synopsis
While the effects of temperature on nerve conduction have been studied by several investigators, there is little in the way of explanation that can be offered for the results obtained. Gasser ( '31) reported the temperature coefficient of the action potential of frog nerve to be large and positive. His observations indicated that the spike declined sharply below 15-20°C with conduction failing in the neighborhood of 5°C. Schoepfle and Erlanger ( '41), working on single fibers in a small branch of the peroneal nerve of the frog, found the temperature coefficient of the spike to be small and negative.
Cooling from 25" to 8°C increased the spike amplitude by a factor of 1.2. Lorente de N6 ('47) observed that when'the