The action of tolbutamide on rat diaphragm
โ Scribed by J. J. Connon
- Book ID
- 118295986
- Publisher
- Springer-Verlag
- Year
- 1969
- Tongue
- English
- Weight
- 188 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1863-4362
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The effects of sodium cyanide (NaCN) were investigated on the contractile and electrophysiological properties of rat diaphragm muscles in vitro. Sodium cyanide (0.1-1.0 mM) produced an initial potentiation of directly elicited twitch tensions, followed by a slow progressive depression. The potentiat
## Abstract The inotropic action of tolbutamide previously demonstrated in vitro was evaluated in 15 nondiabetic subjects during diagnostic cardiac catheterization. Following bolus injection of 250 mg of tolbutamide intravenously, a rise of serum insulin and a slight fall of serum potassium were ob