The action of bile salts on fluid and glucose movement by rat and hamster jejunum,in Vitro

✍ Scribed by Faust, Robert G. ;Wu, Shih-Min Liu

• Publisher: Wiley (John Wiley & Sons)
• Year: 1965
• Tongue: English
• Weight: 1017 KB
• Volume: 65
• Category: Article
• ISSN: 0095-9898
• DOI: 10.1002/jcp.1030650318

✦ Synopsis

Everted sacs of rat and hamster jejunum were used to measure, simultaneously, fluid and glucose movement in the presence of various concentrations of bile salts. Low concentrations of sodium taurocholate or glycocholate did not affect the rates of fluid absorption or transport by either rat or hamster jejunum. Under these conditions, in some cases, while glucose absorption was unaffected, glucose transport was inhibited. High concentrations of bile salts reduced fluid and glucose absorption and transport by both rat and hamster jejunum. Although the transport of glucose against a concentration gradient is completely inhibited at low concentrations of bile salts with rat jejunum, it still occurs with hamster jejunum even in the presence of high bile salt concentrations. In the absence of glucose i n the incubation medium, the rates of fluid absorption by rat and hamster jejunum