The action of a calcitonin gene-related peptide antagonist in human skin
✍ Scribed by N. A. Hayes; C. B. Bunker; I. Marshall; P. M. Dowd; J. C. Foreman
- Publisher
- SP Birkhäuser Verlag Basel
- Year
- 1993
- Tongue
- English
- Weight
- 181 KB
- Volume
- 38
- Category
- Article
- ISSN
- 1420-908X
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In normal human subjects (n = 6), blood flow in the common carotid artery, assessed with an ultrasonic duplex-scanning unit, was increased up to 152% of basal levels by 60-min infusions of human calcitonin gene-related peptide I (alpha CGRP) 80 pmol.kg-1.h-1, but it was not affected by 20 pmol.kg-1.
During postnatal development, the expression of calcitonin gene-related peptide (CGRP) and its mRNA was investigated in the superior olivary complex of the hamster in order to better understand its role in the development of the efferent olivocochlear (OC) pathway. Although both the peptide and its