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The Actin Cytoskeleton Dynamically Associates with T-Cell Receptor Clusters

✍ Scribed by Smoligovets, Alex; Smith, Adam; Wu, Hung-Jen; Petit, Rebecca; Groves, Jay

Book ID
119206988
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
37 KB
Volume
98
Category
Article
ISSN
0006-3495

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## Abstract Activation of phagocytic NADPH oxidase requires association of its cytosolic subunits with the membrane‐bound flavocytochrome. Extensive phosphorylation of the p47^__phox__^ subunit of NADPH oxidase marks the initiation of this activation process. The p47^__phox__^ subunit then transloc