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The acid-mediated ring opening/cyclisation reaction of N-benzyl-α-aryl-azetidinones

✍ Scribed by Frank D. King; Stephen Caddick

Book ID
119375774
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
251 KB
Volume
68
Category
Article
ISSN
0040-4020

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## Abstract The primary‐amine‐initiated polymerization of __α__‐amino acid __N__‐carboxyanhydride (NCA) is a widely‐used and promising way to synthesize polypeptide‐involved materials with various applications. The nucleophilic attack mechanism, also known as normal amine mechanism of ring opening