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The acetylcholine releaser linopirdine increases parietal regional cerebral blood flow in Alzheimer’s disease

✍ Scribed by Christopher H. van Dyck; C. Huie Lin; Rhonda Robinson; Janet Cellar; Eileen O. Smith; J. Craig Nelson; Amy F. T. Arnsten; Paul B. Hoffer

Publisher
Springer
Year
1997
Tongue
English
Weight
467 KB
Volume
132
Category
Article
ISSN
0033-3158

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Regional cerebral blood flow (rCBF) was studied in nine patients with Alzheimer's disease before and after trestment with tacrine. A small but significant improvement in cognitive functioning on the drug was not accompanied by significant changes in rCBF for the group as a whole. However, when the a