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The abnormality of peroxisomal membrane proteins in Zellweger syndrome

✍ Scribed by J. Aikawa; S. Ishizawa; K. Narisawa; K. Tada; S. Yokota; T. Hashimoto


Publisher
Springer
Year
1987
Tongue
English
Weight
204 KB
Volume
10
Category
Article
ISSN
0141-8955

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Peroxisome biogenesis disorders (PBD) are a heterogeneous group of autosomal recessive neurodegenerative disorders that affect multiple organ systems. Approximately 80% of PBD patients are classified in the Zellweger syndrome spectrum (PBD-ZSS). Mutations in the PEX1, PEX6, PEX10, PEX12, or PEX26 ge