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The 9-xanthenylmethyl group: a novel photocleavable protecting group for amines

✍ Scribed by Hong Du; Mary K Boyd

Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
62 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

The 9-xanthenylmethyl group has been investigated as a photocleavable protecting group for amines. Several amines, including two amino acids, were protected in good to very good yield. Irradiation of the protected substrates in neutral solution regenerated the starting amines in good to excellent yield.

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