✦ LIBER ✦

The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription

✍ Scribed by Yang, Zhiyuan; Zhu, Qingwei; Luo, Kunxin; Zhou, Qiang

Book ID: 109776648
Publisher: Nature Publishing Group
Year: 2001
Tongue: English
Weight: 220 KB
Volume: 414
Category: Article
ISSN: 0028-0836
DOI: 10.1038/35104575

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

7SK small nuclear RNA binds to and inhib

7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes

✍ Nguyen, Van Trung; Kiss, Tamás; Michels, Annemieke A.; Bensaude, Olivier 📂 Article 📅 2001 🏛 Nature Publishing Group 🌐 English ⚖ 194 KB

Inhibition of P-TEFb (CDK9/Cyclin T) Kin

Inhibition of P-TEFb (CDK9/Cyclin T) Kinase and RNA Polymerase II Transcription by the Coordinated Actions of HEXIM1 and 7SK snRNA

✍ Jasper H.N Yik; Ruichuan Chen; Rieko Nishimura; Jennifer L Jennings; Andrew J Li 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 544 KB

T-loop phosphorylated Cdk9 localizes to

T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes

✍ Eugene C. Dow; Hongbing Liu; Andrew P. Rice 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 560 KB

## Abstract P‐TEFb functions to induce the elongation step of RNA polymerase II transcription by phosphorylating the carboxyl‐terminal domain of the largest subunit of RNA polymerase II. Core P‐TEFb is comprised of Cdk9 and a cyclin regulatory subunit, with Cyclin T1 being the predominant Cdk9‐asso