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The 5-HT1Areceptor agonist MKC-242 reverses isolation rearing-induced deficits of prepulse inhibition in mice

✍ Scribed by Masaki Sakaue; Yukio Ago; Akemichi Baba; Toshio Matsuda

Publisher: Springer
Year: 2003
Tongue: English
Weight: 247 KB
Volume: 170
Category: Article
ISSN: 0033-3158
DOI: 10.1007/s00213-003-1515-x

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## Abstract We reported previously that (__S__)‐5‐[3‐[(1,4‐benzodioxan‐2‐ylmethyl)amino]propoxy]‐1,3‐benzodioxole hydrochloride (MKC‐242) (3 mg kg^−1^, i.p.), a selective 5‐HT~1A~ receptor agonist, accelerated the re‐entrainment of hamster wheel‐running rhythms to a new 8 hr delayed or advanced lig