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The 5′-Flanking Regions of CYP19A1 and CYP19A2 in Zebrafish

✍ Scribed by Yukinori Kazeto; Shigeho Ijiri; Allen R. Place; Yonathan Zohar; John M. Trant

Book ID: 115588847
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 250 KB
Volume: 288
Category: Article
ISSN: 0006-291X
DOI: 10.1006/bbrc.2001.5796

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## Abstract Cytochrome P450 aromatase (CYP19) is the terminal enzyme in the steroidogenic pathway that converts androgens (e.g., testosterone) into estrogens (e.g., estradiol). Regulation of this gene dictates the ratio of androgens to estrogens; therefore, appropriate expression of this enzyme is