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The 15-deoxy-δ12,14-prostaglandin J2 inhibits LPS‑stimulated inflammation via enhancement of the platelet‑activating factor acetylhydrolase activity in human retinal pigment epithelial cells

✍ Scribed by Park, Won


Book ID
121415130
Publisher
Spandidos Publications Ltd
Year
2013
Tongue
English
Weight
259 KB
Volume
33
Category
Article
ISSN
1107-3756

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Collagenase-3 (matrix metalloproteinase, MMP-13) plays an important role in the degradation of cartilage in pathologic conditions. MMP-13 is elevated in joint tissues in both rheumatoid arthritis (RA) and osteoarthritis (OA). In addition, inflammation-stimulated synovial fibroblasts are able to rele