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The 1,3-dipolar cycloaddition of benzonitrileoxide to conjugated imines

โœ Scribed by Nazar Singh; J.S. Sandhu; Suresh Mohan


Publisher
Elsevier Science
Year
1968
Tongue
French
Weight
102 KB
Volume
9
Category
Article
ISSN
0040-4039

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๐Ÿ“œ SIMILAR VOLUMES


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## Abstract The readily available alkyl dicyanoacetates 1 reacted with the 1,3โ€dipolar reagents arenecarbonitrile oxides 2โ€ฒ and arenecarbonitrile imines 5โ€ฒ to afford 1,2,4โ€oxadiazol and 1,2,4โ€triazol derivatives. The arenecarbonitrile oxides 2โ€ฒ with electronโ€donating groups on the arene ring gave p

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Chiral non racemic carbazate 1, derived from (R)-(-)-phenylglycinol, reacts regioselectively with benzaldehyde or its dimethylacetal to give an azomethine imine. The faci~d, endo/exo and regio selectivities of 1,3-dipolar cycloadditions of this reactive species with various dipolarophiles have been