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The [1,2] and [1,4] wittig rearrangement of optically active allyl α-phenylethyl ether

✍ Scribed by Hugh Felkin; Claude Frajerman


Publisher
Elsevier Science
Year
1977
Tongue
French
Weight
232 KB
Volume
18
Category
Article
ISSN
0040-4039

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Synthesis of optically active aldol deri
✍ Osamu Kitagawa; Shu-ichi Momose; Yoichiro Yamada; Motoo Shiro; Takeo Taguchi 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 68 KB

Treatment of chiral a-benzyloxyor a-propargyloxycarboxamide with tert-BuLi gave b-hydroxycarboxamides (aldol derivatives) in high optical purity through the formation of a-lithiated ethers and the subsquent 1,2-Wittig rearrangement.