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Thalidomide induced alteration in secondary structure of rat embryonic DNA in vivo

✍ Scribed by Dr. Peter H. T. Huang; William G. McBride

Book ID
112213450
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
952 KB
Volume
10
Category
Article
ISSN
0270-3211

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✍ Peter H. T. Huang; William G. McBride πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 25 KB

We have investigated the possibility of [phthalimide carbonyl-14 C]thalidomide and [glutarimide-2-14 C]thalidomide interaction with DNA. In each experiment, groups of pregnant Wistar rats were treated with a labeled compound on day 12 of gestation. The embryos were harvested 24 h later, and dimethlf