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Thalidomide and lenalidomide: Mechanism-based potential drug combinations

✍ Scribed by Vallet, Sonia; Palumbo, Antonio; Raje, Noopur; Boccadoro, Mario; Anderson, Kenneth C.

Book ID
111657006
Publisher
Informa plc
Year
2008
Tongue
English
Weight
419 KB
Volume
49
Category
Article
ISSN
1042-8194

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The introduction of thalidomide, lenalidomide, and bortezomib has changed the way that multiple myeloma (MM) is treated and has greatly improved survival outcomes. These novel agents are often used in combination with conventional drugs, such as dexamethasone, to optimize clinical responses; however