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Thalamo-cortical Sensorimotor Circuit Dysfunction in Multiple Sclerosis: an Integrated Brain Structural and Electrophysiological Assessment

✍ Scribed by ML Dell'Acqua; D Landi; G Zito; F Zappasodi; C Porcaro; D Lupoi; PM Rossini; MM Filippi; F Tecchio

Book ID: 119587450
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 125 KB
Volume: 47
Category: Article
ISSN: 1053-8119
DOI: 10.1016/s1053-8119(09)70966-8

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## Abstract Demyelination and axonal damage are pathologic hallmarks of multiple sclerosis (MS), leading to loss of neuronal synchronization, functional disconnection amongst brain relays, and clinical sequelae. To investigate these properties, the primary component of the sensorimotor network was