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Th2 and Th1 Autoreactive Anti-class II Cell Lines in the Rat Suppress or Induce Autoimmunity

✍ Scribed by P. Pelletier


Book ID
115621395
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
109 KB
Volume
9
Category
Article
ISSN
0896-8411

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The major histocompatibility (MHC) class II genes encode cell surface proteins that bind antigenic peptide for presentation to T-cells. The class II proteins are expressed constitutively on B-cells and EBV-transformed B-cells, and are inducible by IFN-y on a wide variety of cell types. Retinoblastom