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Th1/Th2 balance of peripheral T helper cells in systemic lupus erythematosus

✍ Scribed by Mitsuteru Akahoshi; Hitoshi Nakashima; Yosuke Tanaka; Tsutomu Kohsaka; Shuji Nagano; Eiichi Ohgami; Yojiro Arinobu; Kunihiro Yamaoka; Hiroaki Niiro; Michiya Shinozaki; Hideki Hirakata; Takahiko Horiuchi; Takeshi Otsuka; Yoshiyuki Niho


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
116 KB
Volume
42
Category
Article
ISSN
0004-3591

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X-linked agammaglobulinemia (XLA) is a primary immunodeficiency of the B-cell compartment caused by a defective gene encoding for the tyrosine kinase (btk) essential for B cell differentiation. Affected males undergo recurrent pyogenic infections and deficient immunoglobulin production. Peripheral b